I was wondering whether different brands might cause different side effect. I know the formula is the same but there might be some different minor ingredients, different suppliers, slightly different machines of processes.
Could it even influence effectiveness of the drug? I thought about it because I'm reading the book now and I can see slight differences between it and what I can see here.
Please write what you know about it or maybe even tell us which brand you use and where you bought it.

I really don't think different brands will cause different effects, and I think maybe this was addressed here a while back?? I can't remember, but I believe the differences we're seeing have to do with the fact that people react to medications differently. Some are very sensitive, while others are very tolerant. I'm sure that the doseage is the most important factor, and not the brand. I think this is why some are finding that the standard dose of 50mg might not be ideal for them - just because everyone reacts differently.

We did an informal survey a while back but we had to take it down because it got bogged down with off-topic tangents. rr

Bottom line: While not scientific, we noticed no correlation between source/brand and the nal experience.

I would be shocked if brand difference has any impact whatsoever on our subjective response to naltrexone. In general, and I'm not a pharmacist, brand names are meaningless when dealing with medications, which is why so many drugs are available in generic. Target automatically gives you any generic medication when available. If there were any difference to the quality whatsoever between a brand name and generic, this would not be their policy. Plus, every time my doctor gives me a medication she'll always recommend a generic because it's identical to the brand name but cheaper. So my unscientific, anecdotal experience tells me brand differences are meaningless when it comes to medications in general.

Recently, I read a very eye opening article about generic anti-depressants. I tried to find it just now, but couldn't with a quick google search.

In a nutshell, there are differences with generic drugs. Often, the patent holder for the original drug keeps the "formula" secret even after the patent expires. The generic drug companies have to essentially reverse-engineer the drug.

The article followed several people who had bad reactions/experiences with a generic anti-depressant (can't remember which on) and thought they had some kind of serious illness. Come to find out, a switch to the real deal or a different drug solved the problem.

I'm not saying generic NAL has any problems. Just pointing out that generic drugs can be different than the original.

Q

That's interesting. I am really not qualified to speculate as I don't take many meds so maybe there is a difference between generics and brand names in rare cases... Which doesn't address the original question of whether different brands may cause different subjective reactions to naltrexone, which I still tend to doubt.

You're right Nick. These difference likely are rare otherwise we'd see negative media about generic drugs, which we really don't.

I learned a bit about the differences when planning to titrate off benzo's. Even minor differences in composition or dosage, which you do find among generics, can be important under such circumstances. But nal is has very simple properties and these micro variations should not matter at all for our purposes. The issue of reliability is more important. River uses Sun pharma as its nal supplier. They are a highly reputable manufacturer in India. I know someone looked into alldaychemist and they too use a reputable manufacturer. Someone on MWO had their order confiscated by Canadian customs and was told their Campral was counterfeit. The company was drugdelivery.ca. So it can happen, which is why it's nice to know that members here have found reliable online pharmacies.

Thank you for all the information. Is there anybody who tried different brands?

I had a similar case with an antidepressant a couple of years ago. The generic gave me side effects where the brand name did not. My Doctor is one who suspects that certain drugs are not tolerated well when generic. I had to fork out the big bucks for antidepressants for a couple of years ( which I no longer take thanks to an amino acid program I am on). I am a bit skeptical to buy Nal over the internet in generic form for my boyfriend but with neither one of us having insurance ( me being laid off and him just starting a new job) we will have no choice. I believe River Pharmacy is who some of you use. Is that correct? If so, how is the quality of their Nal? I need to order soon as his binging went from every couple of weeks to every weekend.