I think all4 is right. TSM will block endorphin in anyone who does it but the question is how quickly will extinction come? I think there is a lot more work that needs to be done on this subject. Almost makes me want to go get my PHD

I can only speak for myself and in doing so I need to be careful because I know that what worked so well for me is not necessarily working so well for others and I don't want to make it look like I am insinuating that it's because they are not trying or not capable or not the right type person and so on. It worked for me in this way so that is the way I approach it.
I was very very very well ready to stop drinking I just plain and simply couldn't. Granted I could punch through the withdrawal and sober up for a week or two or even over a month on several occasions but as we all know from the book the alcohol deprivation syndrome would kick in high gear and I'd be back at it full force. I didn't know the term ADS back then but I knew it was happening. Evrery time I stopped drinking in due time I'd start to feel the pent up rage to go back and destroy myself and then it would happen.
I think TSM worked for me right away because I was always looking for a way out. In fact during those times that I would sober up I was always making wild excuses NOT to drink. You all have probably been there. I would make up just as many wild excuses to not drink when I was sober as to drinking when I was not. It's really a form of mental torture when you think about it. So I wanted out. I always wanted out but if I had just one drink then the chase was on and I'd have to keep my levels up or get sick. That's what TSM did for me right away. It stopped the chase. So long before extinction even started to take place TSM worked for me because it stopped the chase.
The chase is coupled with the sickness and this is what interests me greatly. The sickness as I describe it is essentially an overwelming feeling of crisis. After one drink I get my reward and then I start to feel the crisis. In the past I had always thought that this was due to the actual alcohol molecule. The drug itself and what it does to the body but now I know that is not true. The sickness after having one drink and then pausing was actually my brain punishing the body to get more. IT's insane but I know it's true because after my very first experience with TSM I had a mere 3 drinks and felt no sickness at all, no crisis. The reason why is because it was almost as if I drank nothing and therefore the reward was never given and the chase never begun. The alcohol molecule was in my body but it didn't cause this crisis for more so it must have been my own mind doing it.
When I think about this it kind of freaks me out quite frankly and puts a whole lot of other things in perspective like what really does influence us from the outside world? Or is EVERYTHING manifest in our brains?
Ok I'll leave that one for the philosophers.
But suffice to say TSM started working for me immediately because it ended the chase which was the cause of the sickness which lead to drinking more, the cure to the self inflicted disease.
So that's why I responded fast, I found my way out. Now 4 months later I notice other things that are the actual physical process of extinction. I always mention it in this way because it is an actual physical process like when you break a bone and it heals. It's not a psychological process in a cognitive sense (unless my understanding is wrong) but it physically rewires the brain and that indeed takes time and many drinking sessions and probably has a lot to do with an individuals genetics.
So in short my experience with TSM was in two parts. One, the chase. Since the chase and all it's accouterments was the sole reason for my out of control drinking that ended immediately. And two, the physical process of extinction which takes time but I can see it happening now as I am not plagued with chronic thoughts about drinking and my normal triggers have been cemented shut.
So my hypothesis at the moment is that fast responders are people who's main problem with alcohol is the chase, it's associated sickness, withdrawal and so on as a main directive in drinking. IT also can't hurt to have been looking for a way out.
And again I want to be careful and not insinuate anything here. We all drink for a variety of reasons. I didn't drink soley because of the physical addiction I drank because it would mask my daily problems just like anyone else but once it started it was primarily the chase that kept it going and that was way out of control and immediately stopped by TSM.
I always like to use my wife as an example because she's not an alcoholic but does drink most days. She will admit that she drinks because of stress at work and that it's wonderful to relax with a glass of wine or two. That's not a problem but if she thought that was a problem and went to TSM to try and solve it she would be very disappointed as I don't think it would work. Yes sure it will block the endorphin and her buzz will be different but it simply will not have the same power over her as it did someone like myself who was out of control.
That's my take on it.