My side effects were gone after 2-3 weeks. Most people find the side effects go away after a while. I'm not sure if people have tried titrating up from 6 to 12 to 25 to 50, but that may help.

Thanks for responding.

I just felt so defeated trying to stick to TSM but I felt like I was on time release Antabuse! It seems like not much research has gone into super sensitive responders to Nal. I always hated taking codeine - got sick and agitated. Took Valium once for LASIK surgery - made me hyper! Do some of us have unusual wiring?

Last night I had 1 1/2 beers. Today the waves of nausea aren't hitting me like when I had wine. Is there a diff? I'm only on 6.25 but I really did become disinterested after I started the second one. I actually enjoyed my food instead of the booze! I did take a spoonful of Mylanta before my dose. Did that help?

Anyone else on low dose Nal with success? Would love to hear from you. -FA

(I can't believe I used to drink a bottle of wine a day -ugh)