Hi All,

I felt in control and 'cured' after five months. Then on one occasion afterwards I didn't wait the full hour after taking Nal, and subsequently drank too much wine. The week after I forgot to bring Nal to a party and had too much wine again.
I then got a new batch of Nodict from the Canadian Pharmacy, dispatched from India, I think. I waiting an hour and fifteen minutes before having some Champagne and wine but ended up having 12 units. Very sick the next morning.
I'm wondering whether it was the improper use on the previous occasions that has caused my backslide, or is it a problem with Nodict. If it's the latter, should I increase from 50mg to 100mg?
Now waiting on a prescription from Dickson Pharmacy UK having completed the Sinclair Liver Test they posted to me (results were normal).
All replies very welcome.
M.M.

There are some on the forums here who are beginning to suspect that there may be an issue with Nodict and TSM. It's all speculation at this point, but there are a number of people (myself included) who have backslide significantly while using Nodict and/or did not see success with the TSM while using Nodict.

I read one post on the forums where someone suggested chewing the Nodict tablet due to the coating. Perhaps the coating is causing some kind of delayed release of NAL into ones system (I'm just guessing here).

My intention, personally, is to use a different brand of Naltrexone until we get our hands around this suspected issue with Nodict.

Q

Many thanks for your suggestion. I will try and report back Q.
MM.

Like Q said, it's all unproven and only a tenuous hint at this point. Could be wrong. But worth looking carefully at. Ever since starting TSM in October 2009, I never drunk without NAL. Not even a single time. And yet, after having a good plateau (14-21 u/week) on Naltima for at least 80 weeks, I started steadily sliding back on Nodict (23 weeks now and back to 40-50 u/week by now). Unfortunately, I still have tons of Nodict and could not find a place to buy Naltima for less than $8/pill without prescription. Nor I have any idea how I could find a doctor who could prescribe naltrexone to me without that fact ever entering my records.

Yep, your experience is very close to mine. The only difference is that I did drink on Nal maybe 6-7 times during that vacation w/o Nal, but I doubt that would have gotten me re-addicted. I think it was the use of Nodict over a period of time that ultimately resulted in me returned to my pre-TSM levels.

I honestly think it is the coating on the Nodict that is causing the problem. I've done some reading online about coatings and medications and this is typically done to provide a delayed release or long lasting release of a medication. All other forms of Nal I've taken, including the Nal I used while on a Dr prescription here in the US, are uncoated. I think what is going on is that the uncoated Nal provides the 50mg dose instantly (or very quickly) where as the coated Nodict provides the Nal dose over a period of several hours.

Think about it, TSM requires that our bodies receive the 50mg of NAL very quickly so that our adrenal system is locked down within an hour of taking the tablet. Who knows what is going on with a delayed release form of NAL, but I think the experiences of several who have now come forward tell us that Nodict isn't delivering NAL to our bodies fast enough to shut down our adrenal system within the hour we are supposed to wait before we drink. This is why we are getting re-addicted.

If you are going to use Nodict, I would chew it. It is going to taste aweful, but chewing would insure that you get your 50mg dose quickly and not in a time release fashion. In terms of buying Naltima, you can get it at All Day Chemist for $1.60 per tablet plus shipping: https://www.alldaychemist.com/order.php?ipa=415

I have to wonder how many people have thrown in the towel on TSM because of Nodict.....

Let's keep the comments rolling on this and see if we can shed some light on the Nodict issue!

Q

Can you? Without prescription, that is? Two things make me doubtful:

1. ADC web site now states that they require prescription.
2. Apparently there was a change of policy in Indian customs such that they now require that any pharmaceuticals shipped out of the country had had been prescribed if required in the country where the shipment goes. You may or may not remember but Debby from River Pharmacy posted about it here a while ago. River eventually found a solution by, I believe, contracting a doctor in India. Not ADC, to the best of my knowledge.

I just ordered 50 tables from them and received it in under 2 weeks. I can't remember exactly how long, but I know it was under 2 weeks. I literally received the order just over a week ago. There wasn't any mention of a prescription when I ordered my NAL and it arrived, so perhaps All Day Chemist knows a trick that River doesn't

Q

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That's not what the pharmaceutical literature is saying about coated medications. The literature says that coated medications can time delay release from 8-24hr+.

The hour wait isn't to break up the medication, but for our bodies to absorb the 50MG of NAL and transport it to our brains to shut down out adrenal system.

I'm glad to hear that you've not noticed a difference with Nodict. However, could you please provide some clarification. Have you seen success with TSM using Nodict? Or: Have you used another form of NAL and don't see a difference between it and Nodict?

Q