After the up-tick in drinking during week 10, I decided to start week 11 with an AF day, and carefully monitor my consumption on a daily basis so as not to exceed 3 beers on any one day, and no more than 14 beers for the entire week (that’s two US units greater than research based criteria for moderate drinking for women). The minimal effort (i.e, will-power) I put into maintaining vigilance resulted in the following outcome:
Pre-Nal 42
27-May 0.0
28-May 2.2
29-May 2.9
30-May 2.3
31-May 2.0
1-Jun 1.0
2-Jun 2.7
Total 13.2
% redux 68.65%
For any lurkers or newcomers out there reading this post, please keep in mind that my progress may seem more “textbook” that a lot of folks on this board. I think that has to do with the fact that my drinking history, mental and physical health profile is a close match for those subjects who participated in TSM research studies. In order to test the safety and effectiveness an investigational drug has on a specific condition (such as alcoholism), it’s necessary (to the maximum extent possible) to exclude research subjects that have confounding variables, such as simultaneous/contraindicated drug use, serious psychiatric illness (i.e., severe depression and anxiety), and physical ailments that preclude including the subject for medical trials. I’m providing this information because I know many folks frequenting this board and currently following TSM are struggling with slow progress because they don’t meet the “research subject criteria“ -- and may feel that other folks moving along at a faster clip is cause for doubting the efficacy of TSM extinction protocol -- thus, giving up on the program too soon.
As has been mentioned previously on this board, we’re all serving as “real-world” lab rats, and the data provided from the long-term experiment with TSM will be invaluable to others who have yet to pursue the cure. Speaking in the capacity of a real-world lab rat (and self-identified research junkie), I believe it’s imperative that all newcomers understand the huge variance in the time progression to ultimate success with TSM, and not have unreasonable expectations when they begin the program -- especially if they do not meet “test-subject” criteria described above.
Those of you currently following TSM, and considering quitting due to Naltrexone side effects, should know that I've been following a "modified" TSM protocol using 25mg of Naltrexone one hour before drinking (rather than the usual recommended dosage of 50mg). I'm doing so based on Dr. Eskapa's response to my question regarding the "Duration of Opioid Blockade in the Receptors by Naltrexone @
viewtopic.php?f=15&t=339. Accordingly, if you discover you can tolerate 25mg, and it's effective for you, there appears to be no reason (either financially or physically) to use a greater dosage.