Hi Dr Eskapa, I posted the following and was advised to pose it is a question to you direct:-

Hi everyone. I have noticed over the last week or so a definite change in my mood. It just feels really flat and I feel quite disinterested in all areas of my life. It's a sort of listlessness. My husband has remarked I seem to be withdrawn and I can understand that. I have read somewhere that Nal can cause dysphoria (general low mood) and believe this is maybe what I am experiencing. I don't feel really depressed or anxious (been there and can identify it). Has anyone else experienced this? If so, does it pass?

Any advice gratefully received. Thanks. Shasha

PS: I would just to add that I am committed to TSM as my chance to release myself from alcohol addiction. I can definitely live with this for a while as the alternatives are so much less attractive. Also I have read Robert's post regarding this and have checked out the Vaults of Erowid section on Nal (bit odd). My feeling is nothing like as intense as described.


Thanks for your time and consideration.

Low mood is not a general side-effect associated with naltrexone. Did you ever experience similar 'low moods' before starting naltrexone? Or is this something specific to the medication?

Hi Dr Eskapa, thanks for your response. I have suffered with depression on and off for many years (probably mostly alcohol related). In retrospect, I have felt similar to this, but not for several years. I expect my mood will lift naturally when my alc. consumption reduces. I am only in week three of TSM and am drinking more than normal (as experienced by many others). Thanks for your interest and for your book, which is brilliant.