Joe,

I have had a slight nal over drinking beer, so it has nothing to do with what I drink. I would get vertigo before TSM and a feeling that I was swimming (after an entire day in the pool I would feel that way) but it was always allergy season, so it could have been my allergies or the combo of the two (I have had vertigo without drinking a thing).

I never experimented with liquor until I stated having control, so I am not sure if a nal over would or would not happen. I drink hard liquor so rarely now and I am not up to finding my threshold on it; however, I am sure one day I will have one hard liquor drink and the next morning I will have a nal over.

That is a very good link; however, I prefer reading the actual research, but that does intrigued me. It surprises me how many times websites will post "studies" and have their own interpretation on it but do not have the link to the study for the reader to come to their own conclusion. I have to google the for the research only to find out they have misrepresented the study (or a company funded the study) to serve the interest of the article/company. And then sometimes the research done is questionable for one reason of another.

However, if side effects that linger are caused by the bodies lack of ability to process the 6-b-naltrexol it wouldn't matter how the nal was given (I could be wrong, I will look into it). I think this is a really interesting and food for thought.
This reminds of something that Generic posted about his pre TSM hangover. "I had trouble seeing and my brain was doing this thing I called "the record skipping," which is really hard to explain... but was an immediate, jarring, and terrifying change in mental state. An acute switch between fuzzy disconnectedness and hyper-awareness that made me feel like there was something wrong inside my head" Maybe it isn't exactly what you are experiencing, but it made me think of his post. I haven't looked to see if he experienced a nal over and what they were like.

I think nal and/or TSM is just starting to blossom into it own way and as time proceeds we will find a lot more changes in the future. For how many times have you seen a proven theory in practice only for it to change years later (CPR comes to mind). I will be interested how things will advance 10 years from now.

"However, if side effects that linger are caused by the bodies lack of ability to process the 6-b-naltrexol it wouldn't matter how the nal was given..."

What I'm seeing seems to imply that the conversion rate to 6b is lower than for oral forms, so the body might be able to keep up with eliminating it at the lower conversion rate. 6b is primarily eliminated via the kidneys (see page 211, The Cure for Alcoholism). NB, for depot injections the dose given is usually around 380mg and it's expected to last for a month, though it's encapsulated for slow release. WRT the Micro Needle delivery, it seems we'd need a different dose as for TSM, you don't really want the stuff hanging around at therapeutic levels for 3 days, per the book it needs to rise and fall.

I tend to prefer the studies too, but as you mention their premise might be questionable, or the window of time and the particular focus of the study might render it less than useful for our purposes. These other articles can be a good "lead" though. After seeing the one I linked to, I found some studies that covered Micro Needle delivery of Naltrexone, but I haven't had time to give them a good look over.

Joe,

That micro needle study was done only on 9 patients and three were given a placebo. It was conducted over a 72 hour time frame and then a few weeks later to find out the micro needle spot was on their arms.

As far as the other methods, I am unsure how a person who metabolizes 6b differently would be affected if (at all) for the research isn't there for me to find. Think about it, they didn't even come to the conclusion about the side effects until years later.

I think if I had my choice of being deathly ill on oral naltrexone regardless of the dose or a time released pellet (or any other delivery method) I would take the other delivery methods and deal with the naltrexone being in my system instead of being an alcoholic. Maybe I have done just too much research on the subject.