Oh Newlife - your post made me tear up !!! Thank you so much - it so helps to have support here !! Everyone understands ! I have just come in for a break from the garden and am so enjoying it out there - laughed at it being almost too hot where you are to be outside already - we have not even had our last frost yet !!! LOL With the closing for the new house being this week I am digging bulbs to take with us - just in case the new people (when we get a buyer) do not garden!! I love being in the garden - it really is part of my soul! Unfortunately taking a Guinness out with me is too ... LOL

Thank for being here for me my friend .....

Hugs, Maggie xx

Here what is Antabuse (Dysulfiram) and how it work with Alcoholic (from Wikipedia):

Under normal metabolism, alcohol is broken down in the liver by the enzyme alcohol dehydrogenase to acetaldehyde, which is then converted by the enzyme acetaldehyde dehydrogenase to the harmless acetic acid. Disulfiram blocks this reaction at the intermediate stage by blocking acetaldehyde dehydrogenase. After alcohol intake under the influence of disulfiram, the concentration of acetaldehyde in the blood may be five to 10 times higher than that found during metabolism of the same amount of alcohol alone. As acetaldehyde is one of the major causes of the symptoms of a "hangover", this produces immediate and severe negative reaction to alcohol intake. Some five to 10 minutes after alcohol intake, the patient may experience the effects of a severe hangover for a period of 30 minutes up to several hours. Symptoms include flushing of the skin, accelerated heart rate, shortness of breath, nausea, vomiting, throbbing headache, visual disturbance, mental confusion, postural syncope, and circulatory collapse.

Disulfiram should not be taken if alcohol has been consumed in the last 12 hours.[5] There is no tolerance to disulfiram: the longer it is taken, the stronger its effects.[citation needed] As disulfiram is absorbed slowly through the digestive tract and eliminated slowly by the body, the effects may last for up to two weeks after the initial intake; consequently, medical ethics dictate that patients must be fully informed about the disulfiram-alcohol reaction.[6]

A nine-year study published in 2006 found that incorporation of supervised disulfiram and a related compound calcium carbimide into a comprehensive treatment program resulted in an abstinence rate of over 50%.[7]

Disulfiram does not reduce alcohol cravings, so a major problem associated with this drug is extremely poor compliance. A classic study by Fuller (1986) that followed chronic alcoholics for a period of one year found no statistically significant differences in abstinence rates between the group that received disulfiram and the group that only received counseling. The reason for this finding was that only 20% of subjects in disulfiram group were estimated to be in good compliance with the drug regimen.[8] Methods to improve compliance include subdermal implants, which release the drug continuously over a period of up to 12 weeks, and supervised administration practices, for example, having the drug regularly administered by one's spouse.

Although disulfiram remained the most common pharmaceutical treatment of alcohol abuse till the end of the 20th century, today it is often replaced or accompanied with newer drugs, primarily the combination of naltrexone and acamprosate, which directly attempt to address physiological processes in the brain associated with alcohol abuse.


Hope that help.

Hi there ghaunt - thanks for posting and I laughed (in a nice way) at your following my thread ....I do not think I am the best person to follow !! I understand about you thinking I should not take AB for my AF days but I really needed to have some AF time and if AB will help, then I shall do that - the effect of AB only lasts two weeks if one has been taking it continuously for some time - to take 1/4 tab now and then is not going to stay in my system for two weeks ! And I did need to force the AF days - it is a personal thing and I knew that I really needed to do it.

You said that you started Nal last Saturday - how are you doing? Please do start a progress thread - they are so helpful! It is good to see you here and let us know how you are doing .....

hugs, Maggie x

Ghaunt - sorry - I have just posted and then saw that you had posted about AB - but I am going to leave my post - off to read your post now.

Hugs, Maggie x

AB can work for some people - it stops that argument in their head.

I personally don't agree with playing around with it, I think that's dangerous BUT if it helps a person stay AF then that is great.

UKB - I am not playing around with it. I think long and hard before taking it. I take less than 1/4 of a tab - I actually put it in a cutter thing and probably end up taking about 1/8th but in my head any amount stops me drinking. I needed to have some AF days ... and if this is how I do it then so be it.

hi Ghaunt2,

welcome to the forum & TSM

the interaction with opiates is well-known. Benadryl isn't an opiate, so it's not an issue

if you haven't seen the "The Cure for Alcoholism" book, which has lots of information about Naltrexone & TSM, you can read/download a copy here:

https://www.dropbox.com/s/60fs7gmvbyzs1kk/Cure%20for%20Alcoholism.pdf?dl=0

all the best

-badger

Not a problem, Maggie, anytime. Hope you will have a good nights sleep tonight. hugs Newlife

Thank you Badger. I downloaded it. I was wondering where I have to find this book because I saw people talking about it almost everywhere I go on this forum. That will help me to understand a lot more.

Maggie, you don't have to be sorry. Just take it for a grain of salt. If you know what you do, it should be fine.

LOL. I just read it at the beginning of the book. I think you read it too Maggie. You send it to your family if I'm true.
Here the passage:
"Disulfiram. You are in treatment because you cannot resist drinking. Now, without doing anything to improve your ability to resist drinking or to reduce your craving, the facility’s doctors may put you on a prescription of disulfiram (Antabuse®), where if you do what every fiber of your body insists you must do—drink alco-hol—you will suffer agonizing torture and may even die. You must face this ordeal every day for the rest of your life. The disulfiram will do nothing to abate your craving, and if you ever stop taking the disulfiram, your craving will probably be greater than it was before you started taking it.*"

Ok, I'll stop bugging you... See you later.