Hello,

I am new to the Sinclair Method.

I read that Naltrexon should be taken 1 hour before drinking alcohol - and days where you don't drink you don't take Naltrexon.

How about the dosis? I read into the information coming with ReVia that you may start with a half a pill (25mg) - would you start with 25mg or 50mg ?

What worries me a bit about Naltrexon is the interaction it may have with Bupropion that I am also taking. Bupropion is build very much like an amphetamin - I would guess Naltrexon would block this effect totally.

I used Naltrexon a year back for a few days (taking it in the morning every day) and I started to have real sleep problems. Because of its half-live it seems it stays into the body a lot longer than your actual alcohol %o in your bood.

(Half life is 72-108 hours, so if I take 50mg then after 48 hours still 70-80% of my opiatreceptor is blocked).

Thanks for any suggestions,

Welcome Craving!

The recommended dosage for use with the Sinclair Method is 50mg, starting with 25mg for a couple of days to build up to 50mg. People have differing levels of sensitivity to medications. I personally had no problem, and I also take Bupropion (450mg per day). I had no trouble with interactions.

The typcal side effects for Naltrexone are sleepiness, nausea, feeling 'spacey' and headaches. Some people here had a real hard time at first, but the symptoms generally subside over time. I would suggest you take it slow - make SURE you don't take the full 50mg right away. See how your body tolerates the 25mg first.

The members here are extremely supportive, and will help however they can. Best of luck to you, and keep posting!

Dear KrazyKris,

Thank you for your fast reply.

I will give it a try with 25mg ReVia 1 hour before drinking. Have not been drinking for a couple of days and got very strong craving right now.

A side note about Bupropion : Before taking Bupropion I only drank alcohol occasionly and could not really handle drinking a lot. Since taking Bupropion I noticed I am not getting sick of drinking and I can "enjoy" it more - which is very the problem hooks in.

I do not want to get off Bupropion though. Helped me to quit smoking - and right now using it to fight depression.

Will give Naltrexon tomorrow a try.

Thanks for the warm welcome!

You mentioned you used naltrexone a while back. Did a doctor start you on it and was it to stop drinking? Did the dr. recommend abstinance. Would you mind sharing a little information about your experience with nal and how you came upon the Sinclair Method?

Of course, ONLY if you don't mind.

We welcome you here and wish you all the very best!

bb

I got Naltrexone via an online pharmacy - never seen a doctor. I started drinking about 3 years ago and I noticed soon that something is 'different' with me.
One of the attempts to stop the habbit to come as big as it is now was getting naltrexone and staying without drinking.

Sadly I failed on that one. Now that I see my habbit is getting out of control (last week i had a day drinking a 3/4 of a whisky bottle in a day!) I was searching for Naltrexone - as I still have it laying around here. On Wikipedia I read the first time about the Sinclair Method. It sounds interessted - mainly for its course of action. I quit smoking also continue smoking ... it appears to me at this point much more logical to let the body understand itself the incorrect pattern it has learned and let it fix it by itself.

When trying Naltrexone a year ago I was feeling very strange - like not beeing able to sleep. A little bit like now, now that I have not drunk for some days. Maybe the bad experience with Naltrexone is not related to itself - but to the withdrawel from alcohol. (The original therapy with Naltrexone suggest to not drink any alcohol).

I hope to get my drinking under control before social and/or work problems start.

Thanks for the welcome!

Thanks for the information. I hope this journey will be successful for you this time. I am only in week 3 and I am so very excited - for there is hope for all of us! And the thought of losing the craving is fantastic.

I have been classic in that my symptoms were worse in the first week. Now aside from some fatigue I have none left. In fact, I may even be sleeping better now than pre Sinclair. Craving, try to get through at all costs and don't give up! Although it takes months for this to work, I am already enjoying very subtle changes that I am very happy about. I am sure if you read some of the comments you will become aware of these.

Take care and best of luck to you!

Thanks bamabeachin for your motivating words.

I am defintely in to fix this now. This time I can give my body what he thinks he needs ... so the abort rate must be quite low.

Take care and the best of luck to you!

I took 2 hours ago my first 25mg dose and started to drink since 1 hour.
I start to feel sick - nausea. The way I am feeling I am not sure if I can finish the bottle of wine that I have opened.

Mainly because I fear I will all puke it up.

Amazing I managed to drink a full bottle.

So 13.5% x 750 ml = 101.25 ml alcohol

101.25 ml / 17.7 ml = 5.7 units


I do not feel like more ... lets see if I can manage to keep that into my stomach without puking!!

Welcome to both of you & hang in there!