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selincro nalmefene
http://www.thesinclairmethod.com/community/viewtopic.php?f=20&t=4644
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Author:  fiddleplayer [ Thu Jan 28, 2016 2:02 pm ]
Post subject:  selincro nalmefene

Has anyone had experience with both Naltrexone and Nalmefene? I read that the latter has less possibility of liver damage but are there other differences? Also is it available in the US?

Thanks

Robert

Author:  Bardo [ Thu Jan 28, 2016 2:14 pm ]
Post subject:  Re: selincro nalmefene

Nalmefene is metabolized in the kidneys while Naltrexone is metabolized in the liver. They both block the endorphin receptors though the former must be taken two hours prior to drinking. Further, Nalmefene has more noteworthy side effects and if I'm not mistaken still has a patent and thus is profitable for drug companies hence its recent adoption in the U.K. I believe it is available state side. Others may know more.

My understanding is Naltrexone is the preferred option barring any liver conditions. One is not more effective than the other.

Author:  Maggie1929 [ Thu Jan 28, 2016 2:31 pm ]
Post subject:  Re: selincro nalmefene

Fiddleplayer - I was given to understand that liver damage is only possible when one takes higher doses - like 300mg and up. Could be wrong but that is what I heard...

hugs, Maggie x

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