i find that after my first drink of the day i am often sick. Could you please advise whether the naltrexone would still be in my system if i have taken it 1 hour before this, or is it advisable to take another ?

It may be a while before you get a response from Dr. Eskapa as he is not on the board regularly but this has come up before. This thread discusses naltrexone absorption/metabolism
http://www.thesinclairmethod.net/community/viewtopic.php?f=12&t=1718&p=21180&hilit=half+life&sid=c799a8062422beb545cd461070f5846a&sid=c799a8062422beb545cd461070f5846a#p21180

If your concern is you have vomited the naltrexone then try taking your nal 2 hours before you drink with some food to ensure complete absorption even if you then became ill it should be completely absorbed.

(nothing in this post should be construed as medical advice please consult your prescribing physician before altering medication dosing or instructions)

Not giving advice, but I struggle with absorption. Nal is available as a shot--called vivitrol. I am still struggling and fighting, not cured--but I can say it has helped me so far.