WaitingToExhale wrote:
RR: I'm confused about this being 15 years old.
I couldn't find a date on this article, but it states that the patient "got worse in 2000" and then further in the article it references the COMBINE study and notes "eight years later".
Yea, sorry for the confusion. I didn't mean that the article was 15 years old, just the news that naltrexone works for alcoholism.
There was a huge study in (I want to say Pennsylvania U) where they tested the effectiveness of naltrexone on alcoholism in the early 90's. This study was what caused the FDA to allow naltrexone to be used for alcoholism in the first place. I'll have to look up the specifics. It demonstrated NAL to be effective, but the part where it only worked if people disobeyed the instruction to stay abstinent was brushed under the table.
The article rather pointedly doesn't state if Walter Kent drank while he was in the study on naltrexone. I find that to be significant.
N101CS wrote:
At the heart of the matter is the fact that there is no mechanism by which Naltrexone could ever be expected to reduce cravings.
For clarity, you might want to say "naltrexone without drinking". I'm reviewing that paper, too.
