i realize this is an older post, but I have current and previous experience at this intersection of Wellbutrin, Xanex, and Naltrexone, and so will share in case there is information that might help someone else.
Wellbutrin I have been on for 20+ years for depression. There were periods when I thought I was "cured" and so would taper off, only to find myself back in the deep darkness six months later. Now I know not to go off. I cannot speak specifically to its efficacy for ADHD, but the inability to focus is certainly a hallmark of depression, and for me Wellbutrin has been a lifesaver and enabled me to progress in my career and be highly creative/conceptual, including my work as an advertising copywriter, as well as having a number of articles published in national and regional publications.
I am now 12 days into my Naltrexone therapy, and my Dr., who is also the lead psychologist at a local counseling center that specializes in addiction and other CODs (Co-occurring Disorders) had no problem recommending the combination. In fact, he said there is research underway for a drug that would be a combination of Wellbutrin and Naltrexone to be marketed for weight loss - a bonus for me since I've gained about 20lbs this past year. It's true for me as others have said, I don't have much of an appetite right now due to the Nal; but when I am drinking wine at night I then dig into stupid munchie snacks or cheese and crackers.
On a much more serious note, my cautionary Xanex tale: I have also had anxiety/panic attack issues since my mid-twenties, and have been prescribed Xanex many times. In 2008, I lost my job and became a recessionista. My well-meaning care provider gave me the maximum Rx she could for Xanex, since my health insurance would be going away and I was not drinking at the time. I believe it was 400+ .25mg pills, available then in a 3-month dosage thru my mail order benefit.
What started out as responsible use following my lay-off soon became almost recreational, and I was taking 4-6 per day. Still not drinking at the time. I realized I was becoming addicted to them and made arrangements to go to a health spa in AZ for a few days to taper off. (Wish I had that luxury now; I'd check in to Rancho la Puerta in a heartbeat!) Well, I didn't taper off as planned, and ran out of pills since I hadn't brought my huge stash with me. First, I got very, very sick. Like fetal position sick. The night before I was due to fly home, where I was to meet my son at the airport to return home (he had been visiting his dad), I couldn't sleep all night. I had heart palpitations and was nauseous; couldn't eat a thing. It was the most miserable flight ever; I drank 2 liters of water. When I met him at the airport, I was in very rough shape; sick and exhausted. We set out on the 90 minute drive home from the airport and stopped 3/4 of the way at a grocery store. I was so incapacitated I thought I would keel over, could barely pay the cashier, dropped change, but I thought it was just because I hadn't slept. What I didn't realize was that I was going through serious, acute alprozolam withdrawal.
Being in the grocery store was the last thing I remembered until the parametics were pulling me from the driver's seat of my Jeep. My then 14-yr old son had looked up from his iPod or whatever when our Jeep lurched toward a ditch, his mother shaking violently in the driver's seat, her tongue hanging out, unconscious, having a seizure. He somehow grabbed the wheel and got us safely to the shoulder of the road. Then called 911. Police. Fire trucks. Emergency vehicles. They took me by ambulance to the nearest hospital and ran all sorts of tests. I didn't know what day it was or who was President. I couldn't yell them what had happened because I honestly didn't put it together until months later when I was researching alprazolam withdrawal. My primary care provider had NEVER given me any warnings about suddenly discontinuing the use of alprazolam. Nothing about the potential for seizures and/or death. I just thought I was sick.
The silver lining was that they couldn't figure out what had happened since there was nothing in my system. No drugs. No alcohol. So at least I wasn't arrested. But I did get a nice $2,400+ hospital emergency room bill.
When I got home, I resumed taking the Xanex. And felt better the next day.
And being the good addict that I am, I continued using the alprazolam until they were all gone. This time, I had researched how to taper off, and that's when I finally put together what had caused my seizure. But I still didn't taper off enough, and again, I got sick, and was literally in bed for a week, but afraid to fall asleep, for fear I'd have a convulsion. Or just not wake up.
So that was my last experience with that particular class of drugs, at least until I voluntarilly opted for an outpatient detox protocol 15 months ago, but that was a very controlled dosage situation, though equally life threatening; it's the sudden withdrawal that causes most alcholic-related deaths. Or maybe it's driving. Probably driving.
_________________ Pre-TSM: 70-105/week. Back after a 4-year hiatus. Started back on TSM Feb. 2017.
Now...
May 2017: average 14-20 (per week)
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